Non-Specific AGE Inhibition Studies

Benfotiamine

  • Preferred over other thiamine derivatives for AGE inhibition. (Loew 1996)
  • Best suited for therapeutic AGE inhibition due to superior bioavailability. (Greb 1998)
  • Counters advance glycation of plasma protein. (Karachalias 2005)

Pyridoxamine

  • Inhibits advanced glycation reaction. (Onorato 2000)
  • Reduces oxidative stress and AGE formation. (Nagaraj 2002)
  • Inhibits ALEs and AGEs. (Metz 2003)
  • Inhibits conversion of intermediate glycation products to advance glycation end-products. (Voziyan 2003)